Sophie Javerzat, Karine Lecommandoux and Agata Ars, Professor at the University of Bordeaux, Administrative Assistant and Technical Assistant, respectively, have recently joined the MRGM. Warm welcome!
COSTELLO SYNDROME
HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models https://sbm.u-bordeaux.fr/actualites/mise-en-lumiere-de-la-publication-hras-germline-mutations-impair-lkb1ampk-signaling-and-mitochondrial-homeostasis-costello-syndr
PARTICIPATORY RESEARCH INSERM
Inserm's Science and Society department has published testimonies of participatory research on the Inserm website. https://www.inserm.fr/nos-recherches/recherche-participative/ These exchanges are rich in lessons on collaborative research methods with civil society. The added value of this type of research is significant, for the start-up phases of projects, the human dimension of the exercise, and support for material … Continue reading PARTICIPATORY RESEARCH INSERM
Results of the elections to the specialized scientific commissions (CSS) INSERM 2022-2027
Didier Lacombe: CSS2 - Cancerology, genetic diseases. Rodrigue Rossignol: CSS3 – Physiology and physiopathology of large systems.
HCERES 2020-2021
Our research unit, the MRGM (Rare Diseases: Genetics and Metabolism), was evaluated by HCERES in February 2021.
José Antonio Enríquez Seminar | April 14th 2020
The MRGM invites José Antonio Enríquez, a world leading scientist of the mitochondrial research field, to give a lecture on his exciting recent work.
New publication in Oncogene
An additional regulator of mitochondrial bioenergetics discovered by Rossignol’s group: the protein EIF3F stimulates OXPHOS through AMPK. A ChipSeq/Proteomics analysis.
Congratulations!
Caroline Rooryck-Thambo and Giovanni Bénard, two principal investigators at MRGM just have been promoted!
Yeast models of Human mitochondrial disease
Jean-Paul Lasserre is an associate professor at the University of Bordeaux and has recently joined the MRGM team. He will notably develop yeast models for rare diseases.
Tuning the Succinate Dehydrogenase
Using a mitochondrial ubiquitin, Lavie et al. have revealed that the ubiquitin/proteasome system regulates mitochondrial metabolic functions.
Rare Diseases: Genetics and Metabolism 